DNA analysis from human skeletal remains in forensic casework

Application of mtDNA sequence analysis in forensic casework for the identification of human remains.

In four forensic cases of unidentified skeletal remains investigated in the last year, we were able to attach three to missing persons. In one case we could show that the discovered bone sample did not fit to a missing child. The method for mitochondrial DNA analysis for the routine identification of skeletal remains was established in our institute by typing bone samples of defined age obtaine...

Mitochondrial DNA Sequence Analysis - Validation and Use for Forensic Casework.

With the discovery of the polymerase chain reaction (PCR) in the mid-1980's, the last in a series of critical molecular biology techniques (to include the isolation of DNA from human and non-human biological material, and primary sequence analysis of DNA) had been developed to rapidly analyze minute quantities of mitochondrial DNA (mtDNA). This was especially true for mtDNA isolated from challe...

Extraction and Analysis of Ancient DNA from Human Remains of Masjede Kabood Burial Site

FORENSIC SCIENCES Forensic Mitochondrial DNA Analysis: Two Years of Commercial Casework Experience in the United States

Aim. To describe mitochondrial DNA (mtDNA) forensic casework experience in a commercial laboratory in the United States. Methods. Frequency statistics were kept for two years on all aspects of mtDNA forensic cases, including types of clientele, types of samples, levels of sample success and failure, site heteroplasmy, length heteroplasmy, contamination, rates of failures to exclude, and match s...

Age Estimation of Fetal Skeletal Remains from the Forensic Context